Vinegar is wine, which has turned sour either from neglect or from the fault of the vessel. Wine is the honour of immortality or virtue. When this then had been turned sour in Adam, he took and drank it at the hands of the Gentiles. It is offered to him on a reed and a spunge; that is, he took from the bodies of the Gentiles immortality spoiled and corrupted, and transfused in himself into a mixture of immortality that in us which was spoiled.
St. Hillary, quoted by St. Thomas Aquinas, Catena Aurea.